Pharma Quiz 1


Answer: B) Non-selective inhibition of both COX-1 and COX-2 enzymes
Explanation: Ibuprofen works by reversibly inhibiting both cyclooxygenase (COX) enzymes, COX-1 and COX-2, which are responsible for prostaglandin synthesis. This dual inhibition provides its pain-relieving, anti-inflammatory, and fever-reducing effects, but also explains its potential side effects like stomach irritation (from COX-1 inhibition) and cardiovascular risks (from COX-2 inhibition). Unlike selective COX-2 inhibitors, ibuprofen's effect on COX-1 also gives it mild antiplatelet properties at standard doses.

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